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A.Y. Berman, M. Wieczorek, A. Aher, P.D.B. Olinares, B.T. Chait, T.M. Kapoor. “A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division”, J Cell Biol. 2023 Mar 6. Epub 2023 Jan 25. [PMID: 36695784]


S. Hwang, P.D.B. Olinares, J. Lee, J. Kim, B.T. Chait, R.A. King, J.Y. Kang. “Structural basis of transcriptional regulation by a nascent RNA element, HK022 putRNA”, Nat Commun. 2022 Aug 15. [Epub ahead of print] [PMID: 35970830]

J. Du, V.G. Vandavasi, K.R. Molloy, H. Yang, L.N. Massenburg, A. Singh, A.L. Kwansa, Y.G. Yingling, H. O'Neill, B.T. Chait, M. Kumar, B.T. Nixon. “Evidence for Plant-Conserved Region Mediated Trimeric CESAs in Plant Cellulose Synthase Complexes”, Biomacromolecules. 2022 Aug 10. [Online ahead of print] [PMID: 35948425]

J.C. Zinder, P.D.B. Olinares, V. Svetlov, M.W. Bush, E. Nudler, B.T. Chait, T. Walz, T. de Lange. “Shelterin is a dimeric complex with extensive structural heterogeneity”, Proc Natl Acad Sci U S A. 2022 Aug 2. 119 (31):e2201662119. [PMID: 35881804]

S. Balasubramanian, M. Andreani, J.G. Andrade, T. Saha, D. Sundaravinayagam, J. Garzón, W. Zhang, O. Popp, S.I. Hiraga, A. Rahjouei, D.B. Rosen, P. Mertins, B.T. Chait, A.D. Donaldson, M. Di Virgilio. “Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region”, Elife. 2022 Apr 13;11:e75047. [PMID: 35416772]

A.A. Serganov, Y. Udi, M.E. Stein, V. Patel, P.C. Fridy, C.M. Rice, M. Saeed, E.Y. Jacobs, B.T. Chait, M.P. Rout. “Proteomic elucidation of the targets and primary functions of the picornavirus 2A protease”, J Biol Chem. 2022 Mar 30. [Epub ahead of print] [PMID: 35367208]

K.J. Mickolajczyk, P.D.B. Olinares, B.T. Chait, S. Liu, T.M. Kapoor. “The MIDAS domain of AAA mechanoenzyme Mdn1 forms catch bonds with two different substrates”, Elife. 2022 Feb 11;11:e73534. [PMID: 35147499] 


C.W. Akey, D. Singh, C. Ouch, I. Echeverria, I. Nudelman, J.M. Varberg, Z. Yu, F. Fang, Y. Shi, J. Wang, D. Salzberg, K. Song, C. Xu, J.C. Gumbart, S. Suslov, J. Unruh, S.L. Jaspersen, B.T. Chait, A. Sali, J. Fernandez-Martinez, S.J. Ludtke, E. Villa, M.P. Rout. “Comprehensive structure and functional adaptations of the yeast nuclear pore complex”, Cell. 2021 Dec 29. [Epub ahead of print] [PMID: 34982960]

F.D. Mast, P.C. Fridy, N.E. Ketaren, J. Wang, E.Y. Jacobs, J.P. Olivier, T. Sanyal, K.R. Molloy, F. Schmidt, M. Rutkowska, Y. Weisblum, L.M. Rich, E.R. Vanderwall, N. Dambrauskas, V. Vigdorovich, S. Keegan, J.B. Jiler, M.E. Stein, P.D.B. Olinares, L. Herlands, T. Hatziioannou, D.N. Sather, J.S. Debley, D. Fenyö, A. Sali, P.D. Bieniasz, J.D. Aitchison, B.T. Chait, M.P. Rout. “Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape”, Elife. 2021 Dec 7;10:e73027. [PMID: 34874007]

Z. Hakhverdyan, K.R. Molloy, R.I. Subbotin, J. Fernandez-Martinez, B.T. Chait, M.P. Rout. “Measuring in vivo protein turnover and exchange in yeast macromolecular assemblies”, STAR Protoc. 2021 Sep 8. [PMID: 34527957]

Y. Niu, X. Tao, G. Vaisey, P.D.B. Olinares, H. Alwaseem, B. Chait, R. MacKinnon. “Analysis of the Mechanosensor Channel Functionality of TACAN”, Elife. 2021 Aug 10;10:e71188. [PMID: 34374644]

B. Bosch, M.A. DeJesus, N.C. Poulton, W. Zhang, C.A. Engelhart, A. Zaveri, S. Lavalette, N. Ruecker, C. Trujillo, J.B. Wallach, S. Li, S. Ehrt, B.T. Chait, D. Schnappinger, J.M. Rock. “Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis”, Cell. 2021 Jul 16. [Epub ahead of print] [PMID: 34297925]

B. Malone, J. Chen, Q. Wang, E. Llewellyn, Y.J. Choi, P.D.B. Olinares, X. Cao, C. Hernandez, E.T. Eng, B.T. Chait, D.E. Shaw, R. Landick, S.A. Darst, E.A. Campbell. “Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex”, Proc Natl Acad Sci U S A. 2021 May 11. [PMID: 33883267]

M. Wieczorek, S.C. Ti, L. Urnavicius, K.R. Molloy, A. Aher, B.T. Chait, T.M. Kapoor. "Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function.", J Cell Biol. 2021 Mar 1;220(3):e202009146. [PMID: 33496729]

J. Merkenschlager, S. Finkin, V. Ramos, J. Kraft, M. Cipolla, C.R. Nowosad, H. Hartweger, W. Zhang, P.D.B. Olinares, A. Gazumyan, T.Y. Oliveira, B.T. Chait, M.C. Nussenzweig. “Dynamic regulation of TFHselection during the germinal centre reaction.”, Nature. 2021 Feb 3. doi: 10.1038/s41586-021-03187-x. [PMID: 33536617]

J.Y. Kang, E. Llewellyn, J. Chen, P.D.B. Olinares, J. Brewer, B.T. Chait, E.A. Campbell, S.A. Darst. “Structural basis for transcription complex disruption by the Mfd translocase.”, Elife. 2021 Jan 22;10:e62117. [PMID: 33480355]

J. Xu, X. Zhao, F. Mao, V. Basrur, B. Ueberheide, B.T. Chait, C.D. Allis, S.D. Taverna, S. Gao, W. Wang, Y. Liu. “A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.”, Nucleic Acids Res. 2021 Jan 8:gkaa1262. [PMID: 33412588]

M.A. Schureck, J.E. Darling, A. Merk, J. Shao, G. Daggupati, P. Srinivasan, P.D.B. Olinares, M.P. Rout, B.T. Chait, K. Wollenberg, S. Subramaniam, S.A. Desai. “Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake.”, Elife. 2021 Jan 4;10:e65282. [PMID: 33393463]


Z. Hakhverdyan, K.R. Molloy, S. Keegan, T. Herricks, D.M. Lepore, M. Munson, R.I. Subbotin, D. Fenyö, J.D. Aitchison, J. Fernandez-Martinez, B.T. Chait, M.P. Rout. Dissecting the structural dynamics of the nuclear pore complex.” Mol Cell. 2020 Dec 8:S1097-2765(20)30832-7. [PMID: 33333016]

P.D.B. Olinares, J.Y. Kang, E. Llewellyn, C. Chiu, J. Chen, B. Malone, R.M. Saecker, E.A. Campbell, S.A. Darst, B.T. Chait. “Native mass spectrometry-based screening for optimal sample preparation in single-particle cryo-EM.” Structure. 2020 Nov 17:S0969-2126(20)30413-5. [PMID: 33217329]

F.D. Mast, A.T. Navare, A.M. van der Sloot, J. Coulombe-Huntington, M.P. Rout, N.S. Baliga, A. Kaushansky, B.T. Chait, A. Aderem, C.M. Rice, A. Sali, M. Tyers, J.D. Aitchison. "Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality", J Cell Biol. 2020 Oct 5. 219 (10): e202006159. [PMID: 32785687]

Y. Dou, I. Barbosa, H. Jiang, C. Iasillo, K.R. Molloy, W.M. Schulze, S. Cusack, M. Schmid, H. Le Hir, J. LaCava, T.H. Jensen. “NCBP3 positively impacts mRNA biogenesis”, Nucleic Acids Res. 2020 Oct 9. [PMID: 32960271]

Y. Dou, S. Kalmykova, M. Pashkova, M. Oghbaie, H. Jiang, K.R. Molloy, B.T. Chait, M.P. Rout, D. Fenyö, T.H. Jensen, I. Altukhov, J. LaCava. "Affinity proteomic dissection of the human nuclear cap-binding complex interactome", Nucleic Acids Res. 2020 Sep 22:gkaa743. [PMID: 32960270]

J. Chen, B. Malone, E. Llewellyn, M. Grasso, P.M.M. Shelton, P.D.B. Olinares, K. Maruthi, E. Eng, H. Vatandaslar, B.T. Chait, T. Kapoor, S.A. Darst, E.A. Campbell. “Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex”, Cell. 2020 Sep 17;182(6):1560-1573.e13. [PMID: 32783916]

K.J. Mickolajczyk, P.D.B. Olinares, Y. Niu, N. Chen, S.E. Warrington, Y. Sasaki, T. Walz, B.T. Chait, T.M. Kapoor. “Long-range intramolecular allostery and regulation in the dynein-like AAA protein Mdn1”, Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18459-18469. [PMID: 32694211]

J.M. Manning, L.R. Manning, A. Dumoulin, J.C. Padovan, B.T. Chait. “Embryonic and fetal human hemoglobins: structures, oxygen binding, and physiological roles”, Subcell Biochem. 2020;94:275-296. [PMID: 32189304]

J. Kagan, R.L. Moritz, R. Mazurchuk, J.H. Lee, P.V. Kharchenko, O. Rozenblatt-Rosen, E. Ruppin, F. Edfors, F. Ginty, Y. Goltsev, J.A. Wells, J. LaCava, J.L. Riesterer, R.N. Germain, T. Shi, M.S. Chee, B.A. Budnik, J.R. Yates 3rd, B.T. Chait, J.R. Moffitt, R.D. Smith, S. Srivastava . “National Cancer Institute Think-Tank Meeting Report on proteomic cartography and biomarkers at the single-cell level: interrogation of premalignant lesions”, J Proteome Res. 2020 May 1;19(5):1900-1912. [PMID: 32163288]

S.J. Ganesan, M.J. Feyder, I.E. Chemmama, F. Fang, M.P. Rout, B.T. Chait, Y. Shi, M. Munson, A. Sali. “Integrative structure and function of the yeast exocyst complex”, Protein Sci. 2020 Jun;29(6):1486-1501. [PMID: 32239688]

J. Chen, C. Chiu, S. Gopalkrishnan, A.Y. Chen, P.D.B. Olinares, R.M. Saecker, J.T. Winkelman, M.F. Maloney, B.T. Chait, W. Ross, R.L. Gourse, E.A. Campbell, S.A. Darst. “Stepwise Promoter Melting by Bacterial RNA Polymerase”, Mol Cell. 2020 Mar 2. [Epub ahead of print] [PMID: 32160514]

V. Kieuvongngam, P.D.B. Olinares, A. Palillo, M.L. Oldham, B.T. Chait, J. Chen. “Structural basis of substrate recognition by a polypeptide processing and secretion transporter”, Elife. 2020 Jan 14. [PMID: 31934861]

P.D.B. Olinares, B.T. Chait. “Native Mass Spectrometry Analysis of Affinity-Captured Endogenous Yeast RNA Exosome Complexes”, Methods Mol Biol. 2062 (2020) 357-382. [PMID: 31768985]


D. Ardeljan, X. Wang, M. Oghbaie, M.S. Taylor, D. Husband, V. Deshpande, J.P. Steranka, M. Gorbounov, W.R. Yang, B. Sie, H.B. Larman, H. Jiang, K.R. Molloy, I. Altukhov, Z. Li, W. McKerrow, D. Fenyö, K.H. Burns, J. LaCava. “LINE-1 ORF2p expression is nearly imperceptible in human cancers”, Mob DNA. 2019 Dec 31. [PMID: 31892958]

M. Wieczorek, L. Urnavicius, S.C. Ti, K.R. Molloy, B.T. Chait, T.M. Kapoor. “Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex”, Cell. 2019 Dec 13. [PMID: 31862189] [Epub ahead of print]

S. Presslee, G.J. Slater, F. Pujos, A.M. Forasiepi, R. Fischer, K. Molloy, M. Mackie, J.V. Olsen, A. Kramarz, M. Taglioretti, F. Scaglia, M. Lezcano, J. L. Lanata, J. Southon, R. Feranec, J. Bloch, A. Hajduk, F.M. Martin, R. Salas Gismondi, M. Reguero, C. de Muizon, A. Greenwood, B.T. Chait, K. Penkman, M. Collins, R.D.E. MacPhee. “Palaeoproteomics resolves sloth relationships”, Nat Ecol Evol. 2019 Jun 6. [Epub ahead of print] [PMID: 31171860]

R. Hayama, M. Sorci, J.J. Keating IV, L.M. Hecht, J.L. Plawsky, G. Belfort, B.T. Chait, M.P. Rout. “Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations”, PLoS One. 2019 Jun 6. e0217897. [PMID: 31170242]

H. Jiang, M.S. Taylor, K.R. Molloy, I. Altukhov, J. LaCava. “Identification of RNase-sensitive LINE-1 Ribonucleoprotein Interactions by Differential Affinity Immobilization”, Bio Protoc. 2019 Apr 5. [PMID: 31106238]








































2023A.Y. Berman, M. Wieczorek, A. Aher, P.D.B. Olinares, B.T. Chait, T.M. Kapoor. “A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division”, J