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Recent Publications

Recent Reviews


  1. Ramanan V, Scull MA, Sheahan TP, Rice CM, Bhatia SN. New Methods in Tissue Engineering: Improved Models for Viral Infection. Annu Rev Virol. 2014 Nov;1:475-499.

  2. Li MM, MacDonald MR, Rice CM. To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. Trends Cell Biol. 2015 Mar 3. pii: S0962-8924(15)00016-1. doi: 10.1016/j.tcb.2015.02.001. [Epub ahead of print] Review.
  3. Hoffmann HH, Schneider WM, Rice CM. Interferons and viruses: an evolutionary arms race of molecular interactions. Trends Immunol. 2015 Mar;36(3):124-38. doi: 10.1016/ Epub 2015 Feb 20. Review.
  4. Rice CM, Saeed M. Hepatitis C: treatment triumphs. Nature, 2014 Jun 5; 510(7503):43-4. doi: 10.1038/510043a.
  5. Schneider WM, Chevillotte MD, Rice CM.  Interferon-stimulated genes: a complex web of host defenses.  Ann Rev Immunol 2014 32:513-45. Epub 2014 Feb 6.
  6. Shlomai A, de Jong YP, Rice CM.  Virus associated malignancies:  the role of viral hepatitis in hepatocellular carcinoma.  Semin Cancer Biol. 2014 Epub Jan 20.pii: S1044-579X(14)00011-X.
  7. Lindenbach B, Rice CM.  The ins and outs of hepatitis C virus entry and assembly.  Nat Rev Microbiol. 2013 Oct;11(10):688-700. Epub 2013 Sep 10.
  8. Scheel TK, Rice CM. Understanding the hepatitis C virus life cycle paves the way for highly effective therapies.  Nat Med 2013 Jul;19(7):837-49.
  9. Gu M, Rice CM. Structures of hepatitis C virus nonstructural proteins required for replicase assembly and function.  Curr Opin Virol. 2013 Apr;3:129-36. Epub 2013 Apr 16.
  10. Schoggins JW, Rice CM. Innate immune responses to HCV.  Curr Top Microbiol Immunol 2013 369:219-42.
  11. Vaughan AM, Kappe SH, Ploss A, Mikolajczak SA. Development of humanized mouse models to study human malaria parasite infection. Future Microbiol. 2012 May;7:657-65.
  12. Ploss A, Dubuisson J. New advances in the molecular biology of hepatitis C virus infection: towards the identification of new treatment targets. Gut. 2012 May;61 Suppl 1:i25-i35.
  13. Ploss A, Evans MJ. Hepatitis C virus host cell entry. Curr Opin Virol. 2012 Feb;2(1):14-9.
  14. Scull MA, Ploss A. Exiting from uncharted territory: hepatitis C virus assembles in mouse cell lines. Hepatology. 2012 Feb;55(2):645-8.
  15. Dorner M, Ploss A. Deconstructing hepatitis C virus infection in humanized mice. Ann N Y Acad Sci. 2011 Dec;1245:59-62.
  16. Schoggins JW, Rice CM. Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol. 2011 Dec;1(6):519-25.
  17. Biron CA, Rice CM. Innate immunity: trolling, responding and protecting against viral infections. Curr Opin Virol. 2011 Dec;1(6):443-6.
  18. Sheahan T, Jones CT, Ploss A. Advances and challenges in studying hepatitis C virus in its native environment. Expert Rev Gastroenterol Hepatol. 2010 Oct;4(5):541-50. Review.
  19. Rice CM. New insights into HCV replication: potential antiviral targets. Top Antivir Med. 2011 Aug-Sep;19(3):117-20. Review.
  20. Gerold G, Rice CM. Locking out hepatitis C. Nat Med. 2011 May;17(5):542-4.
  21. You S, Murray CL, Luna JM, Rice CM. End game: getting the most out of microRNAs. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3101-2.
  22. Gerold G, Rice CM, Ploss A. Teaching new tricks to an old foe: murinizing hepatitis C virus. Hepatology. 2010 Dec;52(6):2233-6.
  23. Scull MA, Rice CM. A big role for small RNAs in influenza virus replication. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11153-4.
  24. Murray CL, Rice CM. Hepatitis C: An unsuspected drug target.Nature. 2010 May 6;465(7294):42-4.
  25. Branch AD, Rice CM. Antisense gets a grip on miR-122 in chimpanzees. Sci Transl Med. 2010 Jan 6;2(13):13ps1.
  26. de Jong YP, Rice CM, Ploss A. New horizons for studying human hepatotropic infections. J Clin Invest. 2010 Feb 22. pii: 42338. doi: 10.1172/JCI42338.
  27. Ploss A, Rice CM. Towards a small animal model for hepatitis C. EMBO Rep. 2009 Nov;10(11):1220-7. Epub 2009 Oct 16.
  28. Legrand N, Ploss A, Balling R, Becker PD, Borsotti C, Brezillon N, Debarry J, de Jong Y, Deng H, Di Santo JP, Eisenbarth S, Eynon E, Flavell RA, Guzman CA, Huntington ND, Kremsdorf D, Manns MP, Manz MG, Mention JJ, Ott M, Rathinam C, Rice CM, Rongvaux A, Stevens S, Spits H, Strick-Marchand H, Takizawa H, van Lent AU, Wang C, Weijer K, Willinger T, Ziegler P. Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host Microbe. 2009 Jul 23;6(1):5-9.
  29. Oh TS and Rice CM. Predicting response to hepatitis C therapy. J Clin Invest. 2008 Dec 22. pii: 38069. doi: 10.1172/JCI38069.
  30. Murray CL, Jones CT, Rice CM. Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis. Nat Rev Microbiol. 2008 Sep;6(9):699-708.
  31. von Hahn, T., and C. M. Rice. 2008. Hepatitis C virus entry. J Biol Chem. 283(7): 3689-3693
  32. Tellinghuisen, T. L., M. J. Evans, T. von Hahn, S. You, and C. M. Rice. 2007. Studying hepatitis C virus: making the best of a bad virus. J Virol 81:8853-67.
  33. Moradpour, D., F. Penin, and C. M. Rice. 2007. Replication of hepatitis C virus. Nat Rev Microbiol 5:453-63.
  34. Dustin, L. B., and C. M. Rice. 2007. Flying under the radar: the immunobiology of hepatitis C. Annu Rev Immunol 25:71-99.
  35. Lindenbach, B. D., H. J. Thiel, and C. M. Rice. 2007. Flaviviridae: The viruses and their replication, p. 1101-1152. In D. M. Knipe and P. M. Howley (ed.), Fields Virology, Fifth ed, vol. 1. Lippincott-Raven Publishers, Philadelphia.
  36. Lindenbach, B. D., and C. M. Rice. 2005. Unravelling hepatitis C virus replication from genome to function. Nature 436:933-8.
  37. Rice, C. M., and S. You. 2005. Treating hepatitis C: can you teach old dogs new tricks? Hepatology 42:1455-8.
  38. Randall, G., and C. M. Rice. 2004. Interfering with hepatitis C virus RNA replication. Virus Res 102:19-25.
  39. Tellinghuisen, T. L., and C. M. Rice. 2004. The molecular virology of hepatitis C virus, p. p. 455-495, The Liver in Biology and Disease, Principles of Medical Biology, vol. 15. Elsevier Press.
  40. Dustin, L. B. 2004. Reexamining the role of the humoral immune response in control of hepatitis C virus infection. Hepatology 40:756-8.
  41. Lindenbach BD, Rice CM. Molecular biology of flaviviruses. Adv Virus Res 2003;59:23-61.
  42. Evans MJ, Rice CM. Hepatitis C virus replicons finally get to second base. Gastroenterology 2003;125:1892-5.
  43. Rice CM. Virology: fresh assault on hepatitis C. Nature 2003;426:129-31.
  44. De Francesco R, Rice CM. New therapies on the horizon for hepatitis C: are we close? Clin Liver Dis 2003;7:211-42, xi.
  45. Blight KJ, Grakoui A, Hanson HL, Rice CM: The Molecular Biology of Hepatitis C virus. In: Ou JHJ, ed. Hepatitis Viruses. Boston/Dordrecht/London: Kluwer Academic Publishers, 2002; Chapter 4: 81-108.
  46. Tellinghuisen TL, Rice CM. Interaction between hepatitis C virus proteins and host cell factors. Curr Opin Microbiol 2002;5:419-27.
  47. Lindenbach BD, Rice CM. RNAi targeting an animal virus: news from the front. Mol Cell 2002;9:925-7.
  48. Di Bisceglie AM, McHutchison J, Rice CM. New therapeutic strategies for hepatitis C. Hepatology 2002;35:224-31.
  49. Grakoui A, Hanson HL, Rice CM. Bad time for Bonzo? Experimental models of hepatitis C virus infection, replication, and pathogenesis. Hepatology 2001;33:489-95.
  50. Lindenbach BD, and C. M. Rice.: Flaviviridae: The viruses and their replication. In: D. M. Knipe aPMH, ed. Fields Virology. Volume 1. 4th ed. Philadelphia: Lippincott-Raven Publishers, 2001; 991-1041.
  51. Randall G, Rice CM. Hepatitis C virus cell culture replication systems: their potential use for the development of antiviral therapies. Curr Opin Infect Dis 2001;14:743-7.
  52. Reed KE, Rice CM. Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr Top Microbiol Immunol 2000;242:55-84.
  53. Rice CM. Is CD81 the key to hepatitis C virus entry? Hepatology 1999;29:990-2.
  54. Blight KJ, Kolykhalov AA, Reed KE, Agapov EV, Rice CM. Molecular virology of hepatitis C virus: an update with respect to potential antiviral targets. Antivir Ther 1998;3:71-81.


Recent Reviews Ramanan V, Scull MA, Sheahan TP, Rice CM, Bhatia SN. New Methods in Tissue Engineering: Improved Models for Viral Infection. Annu Rev Virol. 2014 Nov;1:475-499.Li