Recent Publications

Alphaviruses

  1. Karki S, Li M, Schoggins JW, Tian S, Rice CM, MacDonald MR. Multiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity. PlosONE 2012 7:e37398. Epub 2012 May 16.
  2. Cristea IM, Rozjabek H, Molloy KR, Karki S, White LL, Rice CM, Rout MP, Chait BT, MacDonald MR. Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication. J Virol. 2010 Jul;84(13):6720-32.
  3. Law LM, Albin OR, Carroll JW, Jones CT, Rice CM, Macdonald MR. Identification of a dominant negative inhibitor of human zinc finger antiviral protein reveals a functional endogenous pool and critical homotypic interactions. J Virol. 2010 May;84(9):4504-12. Epub 2010 Feb 24.
  4. MacDonald MR, Machlin ES, Albin OR, Levy DE.  The zinc finger antiviral protein acts synergistically with an interferon-induced factor for maximal activity against alphaviruses. J Virol. 2007 Dec;81:13509-18. Epub 2007 Oct 10.
  5. Cristea IM, Carroll JW, Rout MP, Rice CM, Chait BT, MacDonald MR. Tracking and elucidating alphavirus-host protein interactions. J Biol Chem. 2006 Oct;281:30269-78. Epub 2006 Aug 8.
  6. Ryman KD, Meier KC, Nangle EM, Ragsdale SL, Korneeva NL, Rhoads RE, MacDonald MR, Klimstra WB. Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells. 2005 J Virol. Feb;79:1487-99.
  7. Guo X, Carroll JW, MacDonald MR, Goff SP, Gao G. The Zinc Finger Antiviral Protein Directly Binds to Specific Viral mRNAs through the CCCH Zinc Finger Motifs.  J Virol. 2004 Dec;78:12781-7.
  8. Bick MJ, Carroll JW, Gao G, Goff SP, Rice CM, MacDonald MR. Expression of the zinc-finger antiviral protein inhibits alphavirus replication. J Virol. 2003 Nov;77:11555-62.
  9. Frolov I, Hardy R, Rice CM. Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis. RNA 2001 Nov;7:1638-51.