September 18, 2018
We're very pleased to welcome Dr. Natalie Omattage to the Chen Lab. For more about current lab members, see our Lab Members page.
September 5, 2018
Zhe Zhang is selected as an honoree of the 2018 Blavatnik Regional Awards!
Zhe is one of two finalists awarded in the life sciences category. He used cryo-electron microscopy to determine the structure of the cystic fibrosis transmembrane conductance regulator, whose mutation is the cause of cystic fibrosis, a debilitating genetic disease. By solving the atomic resolution structures of the inactive and active forms of this chloride channel he has provided fundamental insight into how the channel works, and how mutations abrogate its function. These insights provide a roadmap for development of improved therapies for cystic fibrosis.
June 8, 2018
Dr. Zhe Zhang is awarded the Tri-Institutional Breakout Award for Junior Investigators. Congratulations, Zhe!
April 28, 2017
Dr. Zachary Johnson and Dr. Jue Chen's paper "Structural basis of substrate recognition by the multidrug resistance protein MRP1" is spotlighted in ACS Chemical Biology.
March 17, 2017
Dr. Zachary Johnson and Dr. Jue Chen's paper "Structural basis of substrate recognition by the multidrug resistance protein MRP1" is published in Cell. The full text of the paper is available online and covered in Cell.
March 1, 2017
Chen Lab members have three new papers published or in press: "Structure of the transporter associated with antigen processing trapped by herpes simplex virus" (Oldham, M., Grigorieff, N., and Chen, J.) in Elife; "Structural basis of substrate recognition by the multidrug resistance protein MRP1" (Johnson, J., and Chen., J) forthcoming in Cell and covered at Rockefeller Newswire; and "Molecular structure of the human CFTR ion channel" (Liu, F.Y., Zhang, Z., Csanady, L., Gadsby, D.C., and Chen, J.) forthcoming in Cell.
December 2, 2016
"Atomic structure of the cystic fibrosis transmembrane conductance regulator" (Zhang, Z. and Chen, J.) is published in Cell. Dr. Chen and first author Dr. Zhang's work is the first three-dimensional map of the protein responsible for cystic fibrosis. [Full text.]
April 25, 2016
Congratulations to lab members Dr. Zachary Johnson, recipient of the Jane Coffin Childs Fellowship, and Dr. Hongtu Zhao, recipient of a fellowship from the Human Frontier Science Program!
January 28, 2016
"A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter" (Oldham, M.L., Hite, R.K., Steffen, A.M., Damko, E., Li, Zi., Walz, T., and Chen, J. ) is published in Nature. [Full text.]
August 16, 2015
We're very pleased to welcome Dr. Zachary Johnson to the Chen Lab. For more about current lab members, see our Lab Members page.
"Crystal structured of a polypeptide processing and secretion transporter" (Lin, D.Y., Huang, S., Chen, J.) is published in Nature. [Pubmed]
June 22, 2015
We're so proud of Chen lab member Dr. Ashley Lajoie, who has received a Women and Science Postdoctoral Fellowship from Rockefeller University! Congratulations, Ashley!
May 11, 2015
We are thrilled to welcome three new members to the lab! Zhe Zhang received his doctorate in 2015 from the Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences. Ashley Lajoie completed her graduate research at Brandeis University. Zach Johnson, who received his doctorate from Duke University, will join the lab later this summer. For more about current lab members, see our Lab Members page.
September 10, 2014
We are very excited to be joining the Rockefeller community! Read the press release about Dr. Chen's arrival here.