Thomas Tuschl studies the role of RNA-binding proteins (RBPs) and noncoding RNAs (ncRNAs) in post-transcriptional gene regulation in human cells. He develops genome-wide approaches for the characterization of mRNA-RBP and mRNA-ncRNA interaction networks and their alterations in pathogenic states. These studies may lead to novel prognostic or diagnostic approaches as well as therapeutic approaches.
- Extracellular RNAs
- Ovarian and testicular piRNAs (paper in prep.)
- RNA and DNA sensing during cellular stress responses:
1 (PDF); 2 (PDF)
- Nucleo-cytoplasmic shuttling RNA-binding proteins (current research)
- RNA fluorescence in-situ hybridization