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Welcome to the Hang Laboratory

lab photo in front of 59th St Bridge in bkgrd

Our laboratory is broadly interested in the molecular mechanisms by which chemical signals modulate host-microbe interactions in infection and immunity. These chemical signals (metabolites) may be derived from host metabolism (endogenous metabolites) or the environment (diet, microbiota, therapeutics) and have been challenging to mechanistically elucidate. To dissect the mechanisms that govern host-microbe interactions, my laboratory has 1) developed chemical methods to characterize metabolite-protein interactions and 2) employed key animal models to discover new protective factors from specific microbiota species and elucidated their mechanisms of action. These studies have revealed unpredicted metabolite-protein functions in host immunity and microbial pathogenesis as well as novel microbiota protective factors, which have afforded new therapeutic leads and biomarkers for infection, inflammation and immunotherapy.

My laboratory will be moving to Scripps Research in La Jolla, California (https://www.scripps.edu) starting July 1, 2020. Please use the contact information below if you are interested in joining the laboratory.

Howard Hang, Ph.D.
Professor, Departments of Immunology & Microbiology and Chemistry
Scripps Research
10550 North Torrey Pines Road
La Jolla, California, USA 92037
hhang@scripps.edu

updated: May 1, 2020

Our laboratory is broadly interested in the molecular mechanisms by which chemical signals modulate host-microbe interactions in infection and immunity. These chemical signals (metabolites) may be d