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Neuronal Migration on Astroglia From Heterotypic Brain Regions

To investigate whether the directed movement of neurons along glial fibers is specified by glia in a given brain region, we purified neurons and astroglia from developing cerebellum and hippocampus and analysed the migration of cerebellar granule neuron precursors on hippocampal astroglial fibers. As the neuron moves, the nucleus remains in the rear of the cell. From Gasser UE, Hatten, ME. 1990. Central nervous system neurons migrate on astroglial from heterotypic brain regions in vitro. Proc Natl Acad Sci U S A 87:4543-7
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